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Protein Page:
STXBP4 (human)

Overview
STXBP4 Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose. Interacts with STX4A. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 17q22
Cellular Component: cytoplasm; intermediate filament cytoskeleton; nucleoplasm
Molecular Function: protein binding; syntaxin binding
Biological Process: protein stabilization; response to DNA damage stimulus
Reference #:  Q6ZWJ1 (UniProtKB)
Alt. Names/Synonyms: FLJ16496; MGC149829; MGC50337; STX4-interacting protein; STXB4; STXBP4; Synip; syntaxin 4 interacting protein; Syntaxin 4-interacting protein; syntaxin binding protein 4; Syntaxin-binding protein 4
Gene Symbols: STXBP4
Molecular weight: 61,662 Da
Basal Isoelectric point: 5.12  Predict pI for various phosphorylation states
CST Pathways:  Insulin Receptor Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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STXBP4

Protein Structure Not Found.
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