a Ca(2 )/calmodulin-dependent protein kinase of the PIM family. Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; Oncoprotein; Protein kinase, Ser/Thr (non-receptor); EC 22.214.171.124; Protein kinase, CAMK; CAMK group; PIM family
Molecular Function: ATP binding; protein binding; protein serine/threonine kinase activity
Biological Process: apoptotic mitochondrial changes; cell proliferation; G1/S transition of mitotic cell cycle; male meiosis; negative regulation of apoptosis; negative regulation of cell proliferation; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; protein stabilization; regulation of mitotic cell cycle; response to virus
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.