a protein kinase of the STE20 family. Interacts with androgen receptor (AR), and cotranslocates into the nucleus with AR in response to androgen. Highly expressed in testis and prostate tissues. Note: This description may include information from UniProtKB.
Protein type: Kinase, protein; EC 22.214.171.124; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Nuclear receptor co-regulator; STE group; STE20 family; PAKB subfamily
Molecular Function: ATP binding; protein binding; protein serine/threonine kinase activity; Rac GTPase binding
Biological Process: actin cytoskeleton organization and biogenesis; activation of protein kinase activity; apoptosis; cell migration; cytoskeleton organization and biogenesis; regulation of apoptosis; regulation of MAPKKK cascade; regulation of mitotic cell cycle; regulation of transcription, DNA-dependent; Rho protein signal transduction; stress-activated protein kinase signaling pathway
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.