a protein kinase of the STE20 family. Predominantly expressed in brain. Capable of promoting neurite outgrowth, and thus may play a role in neurite development. Associated with microtubule networks and induces microtubule stabilization. Its subcellular localization is tightly regulated during cell cycle progression. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 22.214.171.124; STE group; STE20 family; PAKB subfamily
Molecular Function: ATP binding; protein serine/threonine kinase activity; Rac GTPase binding
Biological Process: actin cytoskeleton organization and biogenesis; activation of protein kinase activity; apoptosis; cell growth; cell migration; cell proliferation; cytoskeleton organization and biogenesis; learning; locomotory behavior; memory; regulation of apoptosis; regulation of MAPKKK cascade; regulation of mitotic cell cycle; Rho protein signal transduction; signal transduction; stress-activated protein kinase signaling pathway
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.