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Protein Page:
ACTG1 (human)

Overview
ACTG1 Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Belongs to the actin family. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q25
Cellular Component: cytoskeleton; cytosol; extracellular matrix; extracellular space; focal adhesion; membrane; nucleus; plasma membrane
Molecular Function: identical protein binding; protein binding; structural constituent of cytoskeleton; ubiquitin protein ligase binding
Biological Process: cell motility; ephrin receptor signaling pathway; retinal homeostasis; vascular endothelial growth factor receptor signaling pathway
Disease: Baraitser-winter Syndrome 2; Deafness, Autosomal Dominant 20
Reference #:  P63261 (UniProtKB)
Alt. Names/Synonyms: ACTB; ACTG; ACTG1; Actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; actin, gamma 1; cytoskeletal gamma-actin; DFNA20; DFNA26; Gamma-actin
Gene Symbols: ACTG1
Molecular weight: 41,793 Da
Basal Isoelectric point: 5.31  Predict pI for various phosphorylation states
CST Pathways:  Death Receptor Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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ACTG1

Protein Structure Not Found.
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