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Protein Page:
DCK (human)

Overview
DCK Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. Belongs to the DCK/DGK family. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.1.74; Kinase, other; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine
Chromosomal Location of Human Ortholog: 4q13.3-q21.1
Cellular Component: cytosol; nucleus
Molecular Function: deoxycytidine kinase activity; drug binding; nucleoside kinase activity; protein homodimerization activity
Biological Process: purine salvage; pyrimidine nucleoside salvage; pyrimidine nucleotide metabolic process
Reference #:  P27707 (UniProtKB)
Alt. Names/Synonyms: DCK; Deoxycytidine kinase; MGC117410; MGC138632
Gene Symbols: DCK
Molecular weight: 30,519 Da
Basal Isoelectric point: 5.14  Predict pI for various phosphorylation states
Select Structure to View Below

DCK

Protein Structure Not Found.
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