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Protein Page:
SPRY1 (human)

Overview
SPRY1 May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis. Belongs to the sprouty family. Induced by FGF signaling. Note: This description may include information from UniProtKB.
Protein type: Adaptor/scaffold; Inhibitor; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 4q28.1
Cellular Component: cytoplasm; cytosol; Golgi apparatus; nucleoplasm; plasma membrane
Molecular Function: protein binding
Biological Process: negative regulation of epidermal growth factor receptor signaling pathway
Reference #:  O43609 (UniProtKB)
Alt. Names/Synonyms: hSPRY1; Protein sprouty homolog 1; sprouty homolog 1, antagonist of FGF signaling (Drosophila); sprouty, Drosophila, homolog of, 1 (antagonist of FGF signaling); Spry-1; SPRY1; SPY1
Gene Symbols: SPRY1
Molecular weight: 35,122 Da
Basal Isoelectric point: 8.65  Predict pI for various phosphorylation states
CST Pathways:  ErbB/HER Signaling  |  Growth And Differentiation Control by MAPKs
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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SPRY1

Protein Structure Not Found.


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