Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
SSH1 (human)

Overview
SSH1 a dual-specificity phosphatase of the Slingshot family involved in actin reorganization. Its calcineurin-dependent activation dephosphorylates cofilin. Plays a role in later stages of mitosis by dephosphorylating and activating cofilin. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.16; EC 3.1.3.48; Protein phosphatase, dual-specificity
Chromosomal Location of Human Ortholog: 12q24.11
Cellular Component: cytoplasm; nucleoplasm; plasma membrane
Molecular Function: actin binding; phosphoprotein phosphatase activity; protein binding
Biological Process: actin cytoskeleton organization and biogenesis; cell morphogenesis; protein amino acid dephosphorylation; regulation of actin polymerization and/or depolymerization; regulation of axonogenesis; regulation of cellular protein metabolic process
Reference #:  Q8WYL5 (UniProtKB)
Alt. Names/Synonyms: FLJ21928; FLJ38102; hSSH-1L; KIAA1298; Protein phosphatase Slingshot homolog 1; slingshot 1; slingshot homolog 1 (Drosophila); SSH-1L; SSH-like protein 1; SSH1; SSH1L
Gene Symbols: SSH1
Molecular weight: 115,511 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

SSH1

Protein Structure Not Found.


STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein