Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
IWS1 (human)

Overview
IWS1 a Pol II transcription elongation factor essential for mammalian cell proliferation. Interacts with Spt6 and Spt5. Depletion of endogenous human IWS1 results in mRNA processing defects. Three alternatively spliced human isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 2q14.3
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: regulation of mRNA processing
Reference #:  Q96ST2 (UniProtKB)
Alt. Names/Synonyms: DKFZp761G0123; FLJ10006; FLJ14655; FLJ32319; interacts with Spt6; IWS1; IWS1 homolog (S. cerevisiae); IWS1-like protein; IWS1L; MGC126375; MGC126376; Protein IWS1 homolog
Gene Symbols: IWS1
Molecular weight: 91,955 Da
Basal Isoelectric point: 4.58  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

IWS1

Protein Structure Not Found.


STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene