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Protein Page:
IWS1 (human)

IWS1 a Pol II transcription elongation factor essential for mammalian cell proliferation. Interacts with Spt6 and Spt5. Depletion of endogenous human IWS1 results in mRNA processing defects. Three alternatively spliced human isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 2q14.3
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: regulation of mRNA processing; regulation of RNA elongation
Reference #:  Q96ST2 (UniProtKB)
Alt. Names/Synonyms: DKFZp761G0123; FLJ10006; FLJ14655; FLJ32319; interacts with Spt6; IWS1; IWS1 homolog (S. cerevisiae); IWS1-like protein; IWS1L; MGC126375; MGC126376; Protein IWS1 homolog
Gene Symbols: IWS1
Molecular weight: 91,955 Da
Basal Isoelectric point: 4.58  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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