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Protein Page:
hnRNP A2/B1 (human)

Overview
hnRNP A2/B1 Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. Identified in the spliceosome C complex. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IGF2BP1. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding; Spliceosome
Chromosomal Location of Human Ortholog: 7p15
Cellular Component: Cajal body; chromosome, telomeric region; cytoplasm; membrane; nuclear matrix; nucleoplasm; nucleus; ribonucleoprotein complex; spliceosome
Molecular Function: miRNA binding; mRNA 3'-UTR binding; protein binding; RNA binding; single-stranded telomeric DNA binding
Biological Process: gene expression; mRNA export from nucleus; mRNA processing; nuclear mRNA splicing, via spliceosome; primary microRNA processing; RNA transport
Disease: Inclusion Body Myopathy With Early-onset Paget Disease With Or Without Frontotemporal Dementia 2
Reference #:  P22626 (UniProtKB)
Alt. Names/Synonyms: DKFZp779B0244; FLJ22720; heterogeneous nuclear ribonucleoprotein A2/B1; heterogeneous nuclear ribonucleoprotein B1; Heterogeneous nuclear ribonucleoproteins A2/B1; hnRNP A2 / hnRNP B1; hnRNP A2/B1; HNRNPA2; HNRNPA2B1; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; nuclear ribonucleoprotein particle A2 protein; RNPA2; ROA2; SNRPB1
Gene Symbols: HNRNPA2B1
Molecular weight: 37,430 Da
Basal Isoelectric point: 8.97  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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hnRNP A2/B1

Protein Structure Not Found.
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