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Protein Page:
RhoGDI alpha (human)

RhoGDI alpha Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Monomer. Forms a heterodimer with RAC1. Interacts with FER. Belongs to the Rho GDI family. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Cell adhesion; Cell development/differentiation; G protein regulator, misc.; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: cytoskeleton; cytosol
Molecular Function: protein binding
Biological Process: cell motility; negative regulation of apoptosis; negative regulation of axonogenesis; negative regulation of cell adhesion; positive regulation of axonogenesis; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction
Disease: Nephrotic Syndrome, Type 8
Reference #:  P52565 (UniProtKB)
Alt. Names/Synonyms: ARHGDIA; GDIA1; GDIR1; MGC117248; Rho GDI 1; Rho GDP dissociation inhibitor (GDI) alpha; Rho GDP-dissociation inhibitor 1; Rho-GDI alpha; RHOGDI; RHOGDI-1
Gene Symbols: ARHGDIA
Molecular weight: 23,207 Da
Basal Isoelectric point: 5.03  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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RhoGDI alpha

Protein Structure Not Found.
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