Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4. Belongs to the OS-9 family. 4 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Molecular Function: glycoprotein binding; protein binding
Biological Process: ER-associated protein catabolic process; protein retention in ER; protein ubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process; transmembrane transport