a cytoplasmic microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. May mediate the conventional clathrin-mediated uptake of surface receptors. Expressed in the postsynaptic density of neuronal cells. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: EC 220.127.116.11; Hydrolase; Microtubule-binding; Motility/polarity/chemotaxis; Vesicle
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; mitochondrial fission; neurite morphogenesis; receptor internalization; receptor-mediated endocytosis; regulation of axon extension; regulation of nitric-oxide synthase activity; transferrin transport