a cytoplasmic microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. May mediate the conventional clathrin-mediated uptake of surface receptors. Expressed in the postsynaptic density of neuronal cells. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: EC 18.104.22.168; Hydrolase; Microtubule-binding; Motility/polarity/chemotaxis; Vesicle
Molecular Function: GTPase activity; protein binding; SH3 domain binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; neurite morphogenesis; receptor internalization; receptor-mediated endocytosis; regulation of axon extension; regulation of nitric-oxide synthase activity; transferrin transport