one of the three (L, M, and H) intermediate filament proteins that form neurofilaments. Neurofilaments are involved in the maintenance of neuronal caliber. NF-L is the most abundant of the three neurofilament proteins. Defects cause Charcot-Marie-Tooth disease type 1F (CMT1F). Note: This description may include information from UniProtKB.
Molecular Function: identical protein binding; protein binding; protein binding, bridging; protein C-terminus binding; Ras guanyl-nucleotide exchange factor activity; structural constituent of cytoskeleton
Biological Process: anterograde axon cargo transport; axon transport of mitochondrion; intermediate filament organization; MAPKKK cascade; neurofilament bundle assembly; retrograde axon cargo transport