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Protein Page:
tensin 2 (human)

Overview
tensin 2 Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Cell cycle regulation; EC 3.1.3.-; Phosphatase
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: focal adhesion
Molecular Function: kinase binding; protein binding
Biological Process: negative regulation of cell proliferation
Reference #:  Q63HR2 (UniProtKB)
Alt. Names/Synonyms: C1 domain-containing phosphatase and tensin homolog; C1-TEN; C1TEN; DKFZp686D13244; FLJ16320; KIAA1075; TENC1; tensin 2; tensin like C1 domain containing phosphatase (tensin 2); tensin like C1 domain-containing phosphatase; Tensin-2; Tensin-like C1 domain-containing phosphatase; TNS2
Gene Symbols: TNS2
Molecular weight: 152,580 Da
Basal Isoelectric point: 8.67  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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tensin 2

Protein Structure Not Found.
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