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Protein Page:
MDH2 (human)

MDH2 mitochondrial malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. May play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - citrate (TCA) cycle; Carbohydrate Metabolism - glyoxylate and dicarboxylate; Carbohydrate Metabolism - pyruvate; EC; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: 7cen-q22
Cellular Component: mitochondrial matrix; mitochondrion; nucleoplasm; nucleus; plasma membrane
Molecular Function: L-malate dehydrogenase activity
Biological Process: gluconeogenesis; internal protein amino acid acetylation; malate metabolic process; tricarboxylic acid cycle
Reference #:  P40926 (UniProtKB)
Alt. Names/Synonyms: M-MDH; malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase, mitochondrial; MDH; MDH2; MDHM; MGC:3559; MOR1
Gene Symbols: MDH2
Molecular weight: 35,503 Da
Basal Isoelectric point: 8.92  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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