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Protein Page:
ENO2 (human)

ENO2 an enzyme with 2-phospho-D-glycerate hydro-lyase activity. One of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC; Lyase
Chromosomal Location of Human Ortholog: 12p13
Cellular Component: cytosol; extracellular space
Molecular Function: phosphopyruvate hydratase activity
Biological Process: gluconeogenesis
Reference #:  P09104 (UniProtKB)
Alt. Names/Synonyms: 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolyase; ENO2; ENOG; Enolase 2; enolase 2 (gamma, neuronal); Gamma-enolase; Neural enolase; neuron specific gamma enolase; Neuron-specific enolase; neurone-specific enolase; NSE
Gene Symbols: ENO2
Molecular weight: 47,269 Da
Basal Isoelectric point: 4.91  Predict pI for various phosphorylation states
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