Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
LDH-A (human)

LDH-A Homotetramer. Belongs to the LDH/MDH superfamily. LDH family. 5 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - cysteine and methionine; Apoptosis; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - pyruvate; EC; Oxidoreductase
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: cell-cell adherens junction; cytosol; membrane; nucleus
Molecular Function: L-lactate dehydrogenase activity; protein binding
Biological Process: pyruvate metabolic process
Disease: Glycogen Storage Disease Xi
Reference #:  P00338 (UniProtKB)
Alt. Names/Synonyms: cell proliferation-inducing gene 19 protein; GSD11; L-lactate dehydrogenase A chain; lactate dehydrogenase A; lactate dehydrogenase M; LDH muscle subunit; LDH-A; LDH-M; LDH1; LDHA; LDHM; PIG19; proliferation-inducing gene 19; Renal carcinoma antigen NY-REN-59
Gene Symbols: LDHA
Molecular weight: 36,689 Da
Basal Isoelectric point: 8.44  Predict pI for various phosphorylation states
CST Pathways:  Warburg Effect
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script

STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein