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Protein Page:
EIF6 (human)

Overview
EIF6 eukaryotic translation initiation factor 6. Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex. Note: This description may include information from UniProtKB.
Protein type: Nucleolus; Translation; Translation initiation
Chromosomal Location of Human Ortholog: 20q12
Cellular Component: cytoplasm; cytosol; nucleolus; nucleoplasm; nucleus
Molecular Function: protein binding; ribosomal large subunit binding; ribosome binding
Biological Process: maturation of 5.8S rRNA; maturation of LSU-rRNA; mature ribosome assembly; miRNA-mediated gene silencing; miRNA-mediated gene silencing, negative regulation of translation; positive regulation of translation; regulation of fatty acid biosynthetic process; regulation of glycolysis; regulation of megakaryocyte differentiation; response to insulin stimulus; ribosome export from nucleus
Reference #:  P56537 (UniProtKB)
Alt. Names/Synonyms: 2; b; b(2)gcn; B(2)GCN homolog; B4 integrin interactor; CAB; eIF-6; EIF3A; EIF6; eukaryotic translation initiation factor 3A; Eukaryotic translation initiation factor 6; gcn; IF6; integrin beta 4 binding protein; ITGB4BP; p27 beta-4 integrin-binding protein; p27(BBP); p27BBP
Gene Symbols: EIF6
Molecular weight: 26,599 Da
Basal Isoelectric point: 4.56  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

EIF6

Protein Structure Not Found.


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