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Protein Page:
CDC37 (human)

Overview
CDC37 a molecular chaperone that functions in cell signal transduction. Forms complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. Also interacts with androgen receptor. It is thought to play a critical role in directing Hsp90 to its target kinases. Note: This description may include information from UniProtKB.
Protein type: Chaperone
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cytoplasm; cytosol
Molecular Function: chaperone binding; heat shock protein binding; kinase binding; protein binding; protein-tyrosine kinase activity; unfolded protein binding
Biological Process: protein folding; protein stabilization; protein targeting; regulation of cyclin-dependent protein kinase activity
Reference #:  Q16543 (UniProtKB)
Alt. Names/Synonyms: CDC37; CDC37 (cell division cycle 37, S. cerevisiae, homolog); CDC37 cell division cycle 37 homolog; CDC37A; cell division cycle 37 homolog (S. cerevisiae); cell division cycle 37 protein; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co-chaperone Cdc37; p50Cdc37
Gene Symbols: CDC37
Molecular weight: 44,468 Da
Basal Isoelectric point: 5.17  Predict pI for various phosphorylation states
CST Pathways:  Inhibition of Apoptosis
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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CDC37

Protein Structure Not Found.
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