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Protein Page:
VRK3 (human)

VRK3 Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily. 2 human isoforms produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: CK1 group; EC; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor); VRK family
Chromosomal Location of Human Ortholog: 19q13
Cellular Component: cytoplasm; nucleus
Molecular Function: protein phosphatase binding; protein serine/threonine kinase activity
Biological Process: peptidyl-serine phosphorylation; regulation of cell shape
Reference #:  Q8IV63 (UniProtKB)
Alt. Names/Synonyms: Serine/threonine-protein kinase VRK3; vaccinia related kinase 3; Vaccinia-related kinase 3; VRK3
Gene Symbols: VRK3
Molecular weight: 52,881 Da
Basal Isoelectric point: 9.21  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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