an adaptor protein involved in cytokine signal transduction the JAK-STAT cascade. Binds to the SH3 domain of the signal-transducing adaptor molecule STAM (signal transducing adaptor molecule). May play a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Note: This description may include information from UniProtKB.
Protein type: EC 188.8.131.52; EC 3.4.19.-; Protease; Ubiquitin-specific protease
Molecular Function: protein binding; protein domain specific binding; ubiquitin-specific protease activity
Biological Process: cytokinesis after mitosis; JAK-STAT cascade; negative regulation of phosphoinositide 3-kinase cascade; negative regulation of Ras protein signal transduction; positive regulation of cell proliferation; protein deubiquitination