polynucleotide kinase 3'-phosphatase. May be involved in double-strand break repair by non-homologous end joining. Required for normal response to DNA damage by gamma-radiation or camptothecin in S. pombe. Note: This description may include information from UniProtKB.
Molecular Function: ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity; double-stranded DNA binding; nucleotide kinase activity; polynucleotide 3'-phosphatase activity; protein binding
Biological Process: dephosphorylation; DNA damage response, detection of DNA damage; DNA repair; nucleotide phosphorylation; positive regulation of telomerase activity; positive regulation of telomere maintenance via telomerase; response to oxidative stress; response to radiation
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.