the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and preribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-RNA transcription and ribosome assembly. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Helicase; Nuclear receptor co-regulator; Nucleolus; RNA-binding