a structural maintenance of chromosomes (SMC) protein involved in postreplication repair of UV-damaged DNA. Has ssDNA binding activity. Interacts with Rad6 through a conserved ring-finger motif. Rad6 is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Note: This description may include information from UniProtKB.
Protein type: EC 126.96.36.199; Ubiquitin ligase; DNA repair, damage; EC 6.3.2.-; Ubiquitin conjugating system; Ligase
Molecular Function: damaged DNA binding; identical protein binding; ligase activity; polyubiquitin binding; protein binding; protein complex binding; single-stranded DNA-dependent ATPase activity; ubiquitin protein ligase binding; Y-form DNA binding; zinc ion binding
Biological Process: DNA damage response, detection of DNA damage; DNA repair; positive regulation of chromosome segregation; postreplication repair; protein autoubiquitination; protein monoubiquitination; response to DNA damage stimulus; response to UV
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.