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Protein Page:
SUZ12 (human)

Overview
SUZ12 a zinc finger protein. A breakpoint translocation of the cognate gene with JAZF1 has been reported in endometrial stromal sarcoma. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: ESC/E(Z) complex; nucleolus; nucleoplasm; nucleus
Molecular Function: chromatin DNA binding; histone methyltransferase activity; methylated histone residue binding; protein binding
Biological Process: negative regulation of cell differentiation; negative regulation of gene expression, epigenetic; regulation of transcription, DNA-dependent
Reference #:  Q15022 (UniProtKB)
Alt. Names/Synonyms: ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; JJAZ1; Joined to JAZF1 protein; KIAA0160; Polycomb protein SUZ12; suppressor of zeste 12 homolog (Drosophila); Suppressor of zeste 12 protein homolog; SUZ12
Gene Symbols: SUZ12
Molecular weight: 83,055 Da
Basal Isoelectric point: 8.98  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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SUZ12

Protein Structure Not Found.
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