a calcium-binding protein of the calreticulin family. A type I membrane protein of the endoplasmic reticulum .Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. May act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Endoplasmic reticulum; Membrane protein, integral; Motility/polarity/chemotaxis
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; protein folding; protein secretion; synaptic vesicle endocytosis