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Protein Page:
Calnexin (human)

Overview
Calnexin a calcium-binding protein of the calreticulin family. A type I membrane protein of the endoplasmic reticulum .Interacts with newly synthesized glycoproteins in the endoplasmic reticulum. May act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Endoplasmic reticulum; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q35
Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular matrix; membrane
Molecular Function: protein binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; protein folding; protein secretion; synaptic vesicle endocytosis
Reference #:  P27824 (UniProtKB)
Alt. Names/Synonyms: Calnexin; CALX; CANX; CNX; FLJ26570; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90
Gene Symbols: CANX
Molecular weight: 67,568 Da
Basal Isoelectric point: 4.47  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Calnexin

Protein Structure Not Found.
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