Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
MYO6 (human)

Overview
MYO6 a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 6q13
Cellular Component: cell cortex; cell-cell adherens junction; clathrin-coated endocytic vesicle; cytoplasm; cytoplasmic membrane-bound vesicle; cytosol; DNA-directed RNA polymerase II, holoenzyme; endocytic vesicle; filamentous actin; Golgi apparatus; lysosomal membrane; membrane; nuclear membrane; nucleoplasm; nucleus; perinuclear region of cytoplasm; plasma membrane; ruffle; unconventional myosin complex
Molecular Function: actin binding; actin filament binding; ADP binding; calmodulin binding; motor activity; protein binding
Biological Process: actin filament-based movement; DNA damage response, signal transduction by p53 class mediator; endocytosis; intracellular protein transport; positive regulation of transcription from RNA polymerase II promoter; regulation of secretion
Disease: Deafness, Autosomal Dominant 22; Deafness, Autosomal Recessive 37
Reference #:  Q9UM54 (UniProtKB)
Alt. Names/Synonyms: DFNA22; DFNB37; KIAA0389; MYO6; myosin VI; Myosin-VI; Unconventional myosin-6
Gene Symbols: MYO6
Molecular weight: 149,691 Da
Basal Isoelectric point: 8.74  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

MYO6

Protein Structure Not Found.
Download PyMol Script
Download ChimeraX Script


STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene