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Protein Page:
DYNLL2 (human)
rdtyret
p Phosphorylation
ac Acetylation
me Methylation
m1 Mono-methylation
m2 Di-methylation
m3 Tri-methylation
ub Ubiquitylation
sm Sumoylation
ne Neddylation
gl O-GlcNAc
ga O-GalNAc
pa Palmitoylation
ad Adenylation
sn S-Nitrosylation
ca Caspase cleavage
sc Succinylation

Overview
DYNLL2 Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Belongs to the dynein light chain family. Note: This description may include information from UniProtKB.
Protein type: Motor; Microtubule-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q22
Cellular Component: centrosome; cytosol; dynein complex; membrane; microtubule; mitochondrion; myosin complex; nucleus; plasma membrane
Molecular Function: cytoskeletal protein binding; motor activity; protein binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; apoptosis; cellular protein metabolic process; ER to Golgi vesicle-mediated transport; macroautophagy; microtubule-based process; organelle organization and biogenesis; post-translational protein modification; programmed cell death; protein amino acid N-linked glycosylation via asparagine; synaptic target recognition
Reference #:  Q96FJ2 (UniProtKB)
Alt. Names/Synonyms: 8 kDa dynein light chain b; DLC2; DLC8b; DNCL1B; DYL2; Dynein light chain 2, cytoplasmic; Dynein light chain LC8-type 2; dynein, light chain, LC8-type 2; DYNLL2; MGC17810; radial spoke 22 homolog; RSPH22
Gene Symbols: DYNLL2
Molecular weight: 10,350 Da
Basal Isoelectric point: 6.81  Predict pI for various phosphorylation states
Select Structure to View Below

DYNLL2

Protein Structure Not Found.


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Modification Sites and Domains  
Click here to view other types of protein modifications

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       human

 
0 1 S14 VIKNADMSEDMQQDA
0 2 Y32 ATQAMEKyNIEKDIA
0 1 Y41 IEKDIAAyIKKEFDK
0 3 S64 IVGRNFGsyVTHETK
0 198 Y65 VGRNFGsyVTHETKH
1 0 S88 VAILLFKsG______
  mouse

 
S14 VIKNADMsEDMQQDA
Y32 ATQAMEKYNIEKDIA
Y41 IEKDIAAYIKKEFDK
S64 IVGRNFGSyVTHETK
Y65 VGRNFGSyVTHETKH
S88 VAILLFKSG______
  rat

 
S14 VIKNADMSEDMQQDA
Y32 ATQAMEKyNIEKDIA
Y41 IEKDIAAYIKKEFDK
S64 IVGRNFGsyVTHETK
Y65 VGRNFGsyVTHETKH
S88 VAILLFKSG______
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