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Protein Page:
GMCSF (mouse)

Overview
GMCSF Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Cytokine; Secreted
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity
Biological Process: embryonic placenta development; epithelial fluid transport; histamine secretion; immune response; macrophage activation; monocyte differentiation; myeloid dendritic cell differentiation; negative regulation of cytolysis; neutrophil differentiation; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of interleukin-23 production; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of cell proliferation; regulation of circadian sleep/wake cycle, sleep; regulation of gene expression
Reference #:  P01587 (UniProtKB)
Gene Symbols: Csf2
Molecular weight: 16,091 Da
Basal Isoelectric point: 5.84  Predict pI for various phosphorylation states
Select Structure to View Below

GMCSF

Protein Structure Not Found.
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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 1 N83 FEQGLRGNFTKLKGA
0 1 N92 TKLKGALNMTASYYQ
0 1 T116 DCETQVTTYADFIDS
  human

 
S86‑p YKQGLRGsLTKLKGP
T95‑p TKLKGPLtMMASHYK
T119‑p SCATQIItFESFKEN
  rat

 
N86 YKQGLRGNLTKLNGA
T95 TKLNGALTMIASHYQ
T119 DCEIEVTTFEDFIKN
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