Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family. Note: This description may include information from UniProtKB.
Protein type: Secreted, signal peptide; Secreted; Cytokine
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: embryonic placenta development; epithelial fluid transport; histamine secretion; macrophage activation; monocyte differentiation; myeloid dendritic cell differentiation; negative regulation of cytolysis; neutrophil differentiation; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of interleukin-23 production; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of cell proliferation; regulation of circadian sleep/wake cycle, sleep; regulation of gene expression
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.