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Protein Page:
PAK2 (mouse)

Overview
PAK2 a protein kinase of the STE20 family. Critical effector linking RhoGTPases to cytoskeleton reorganization and nuclear signaling. Activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.11.1; Kinase, protein; PAKA subfamily; Protein kinase, STE; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family
Cellular Component: cell-cell adherens junction; cytoplasm; nucleoplasm
Molecular Function: protein binding; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity; protein tyrosine kinase activator activity; receptor signaling protein serine/threonine kinase activity
Biological Process: mitotic cell cycle; negative regulation of apoptosis; peptidyl-serine phosphorylation; phosphorylation; positive regulation of peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of apoptosis
Reference #:  Q8CIN4 (UniProtKB)
Alt. Names/Synonyms: A130002K10Rik; AI836325; D16Ertd269e; Gamma-PAK; KIAA4182; mKIAA4182; OTTMUSP00000028355; p21 protein (Cdc42/Rac)-activated kinase 2; p21-activated kinase 2; PAK-2; PAK-2p27; PAK-2p34; Pak2; Serine/threonine-protein kinase PAK 2
Gene Symbols: Pak2
Molecular weight: 57,930 Da
Basal Isoelectric point: 5.57  Predict pI for various phosphorylation states
CST Pathways:  Growth And Differentiation Control by MAPKs  |  Microtubule Dynamics  |  TGF-ß Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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PAK2

Protein Structure Not Found.
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