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Protein Page:
BCAP31 iso2 (human)

Overview
BCAP31 iso2 May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis. Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB. Ubiquitous. Belongs to the BCAP29/BCAP31 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; integral to plasma membrane; lipid particle; membrane; translocon complex
Molecular Function: protein binding
Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cell structure disassembly during apoptosis; elevation of cytosolic calcium ion concentration; elevation of mitochondrial calcium ion concentration; ER to Golgi vesicle-mediated transport; positive regulation of caspase activity; reduction of endoplasmic reticulum calcium ion concentration
Disease: Deafness, Dystonia, And Cerebral Hypomyelination
Reference #:  P51572-2 (UniProtKB)
Alt. Names/Synonyms: 6C6 antigen; 6C6-AG; 6C6-AG tumor-associated antigen; B-cell receptor-associated protein 31; BAP31; BCAP31; BCR-associated protein 31; BCR-associated protein Bap31; CDM; DXS1357E; p28; p28 Bap31; Protein CDM
Gene Symbols: BCAP31
Molecular weight: 34,752 Da
Basal Isoelectric point: 7.66  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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BCAP31 iso2

Protein Structure Not Found.
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