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Protein Page:
IL17A (mouse)

Overview
IL17A Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: cytoplasm; external side of plasma membrane; extracellular region; extracellular space
Molecular Function: cytokine activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding
Biological Process: cell surface receptor linked signal transduction; defense response to fungus; inflammatory response; positive regulation of interleukin-23 production; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter
Reference #:  Q62386 (UniProtKB)
Alt. Names/Synonyms: CTLA-8; Ctla8; Cytotoxic T-lymphocyte-associated antigen 8; IL-17; IL-17A; Il17; Il17a; interleukin 17A; Interleukin-17A
Gene Symbols: Il17a
Molecular weight: 17,490 Da
Basal Isoelectric point: 9.19  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

IL17A

Protein Structure Not Found.


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Modification Sites and Domains  

Modification Sites in Parent Protein, Orthologs, and Isoforms  
 

Show Multiple Sequence Alignment


 LTP 

LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.


 HTP 

HTP: The number of records in which this modification site was assigned using ONLY proteomic discovery-mode mass spectrometry.


       mouse

 
0 2 T38 QSSACPNTEAKDFLQ
  human

 
S36‑p RNPGCPNsEDKNFPR
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