DNA-dependent ATPase. May modulate chromosome segregation. Interacts with UBR1 and UBR2. Interacts with MCM10; this interaction regulates RECQL4 unwinding activity. Up-regulated in actively dividing cells. Ubiquitously expressed, with highest levels in thymus and testis. Belongs to the helicase family. RecQ subfamily. Note: This description may include information from UniProtKB.
Molecular Function: ATP binding; ATP-dependent 3'-5' DNA helicase activity; bubble DNA binding; four-way junction helicase activity; helicase activity; oxidized purine DNA binding; protein binding
Biological Process: base-excision repair; DNA duplex unwinding; DNA repair; DNA replication; DNA strand renaturation; double-strand break repair via homologous recombination; multicellular organismal development; telomere maintenance