Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5. Ubiquitous. Belongs to the ATG12 family. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Ubiquitin-like modifier
Cellular Component: membrane; pre-autophagosomal structure membrane; protein complex
Molecular Function: APG8 conjugating enzyme activity; protein binding