Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
PhosphoSitePlus
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
AurC (human)

Overview
AurC a member of the AUR family of kinases. May play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. Localized to centrosome from anaphase to cytokinesis. Two splice-variant isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: AUR family; EC 2.7.11.1; Kinase, protein; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 19q13.43
Cellular Component: condensed chromosome; condensed nuclear chromosome, pericentric region; midbody; spindle; spindle microtubule; spindle midzone; spindle pole centrosome
Molecular Function: histone serine kinase activity; protein kinase activity; protein serine/threonine/tyrosine kinase activity
Biological Process: attachment of spindle microtubules to kinetochore; histone modification; positive regulation of cytokinesis; protein amino acid phosphorylation; spindle midzone assembly involved in mitosis
Disease: Spermatogenic Failure 5
Reference #:  Q9UQB9 (UniProtKB)
Alt. Names/Synonyms: AIE2; AIK3; ARK-3; ARK3; AurC; AURKC; Aurora C; Aurora kinase C; aurora-C; Aurora-related kinase 3; Aurora/IPL1-related kinase 3; Aurora/IPL1/Eg2 protein 2; serine/threonine kinase 13 (aurora/IPL1-like); Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; STK13
Gene Symbols: AURKC
Molecular weight: 35,591 Da
Basal Isoelectric point: 8.96  Predict pI for various phosphorylation states
Select Structure to View Below

AurC

Protein Structure Not Found.


STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene