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Protein Page:
DEPTOR (human)

Overview
DEPTOR Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. Note: This description may include information from UniProtKB.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 8q24.12
Cellular Component: intracellular
Molecular Function: protein binding
Biological Process: negative regulation of cell size; negative regulation of protein kinase activity; negative regulation of TOR signaling pathway
Reference #:  Q8TB45 (UniProtKB)
Alt. Names/Synonyms: DEP domain containing 6; DEP domain containing mTOR interacting protein; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; DEP.6; DEPD6; DEPDC6; Deptor; DKFZp564B1778; FLJ12341; FLJ12428; FLJ13854
Gene Symbols: DEPTOR
Molecular weight: 46,294 Da
Basal Isoelectric point: 8.29  Predict pI for various phosphorylation states
CST Pathways:  Insulin Receptor Signaling  |  mTOR Signaling  |  PI3K/Akt Signaling  |  T Cell Receptor Signaling  |  Translation: eIF4E and p70S6K
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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DEPTOR

Protein Structure Not Found.


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