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Protein Page:
RXRG (human)

RXRG Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Belongs to the nuclear hormone receptor family. NR2 subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of Human Ortholog: 1q22-q23
Cellular Component: nucleoplasm
Molecular Function: protein binding
Biological Process: transcription initiation from RNA polymerase II promoter
Reference #:  P48443 (UniProtKB)
Alt. Names/Synonyms: NR2B3; Nuclear receptor subfamily 2 group B member 3; Retinoic acid receptor RXR-gamma; Retinoid X receptor gamma; retinoid X receptor, gamma; retinoid X receptor-gamma; RXRC; RXRG
Gene Symbols: RXRG
Molecular weight: 50,871 Da
Basal Isoelectric point: 7.55  Predict pI for various phosphorylation states
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