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Protein Page:
TRB2 (human)

Overview
TRB2 Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily. Note: This description may include information from UniProtKB.
Protein type: CAMK group; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); Trbl family
Chromosomal Location of Human Ortholog: 2p24.3
Cellular Component: cytoplasm; nucleus
Molecular Function: mitogen-activated protein kinase kinase binding; nucleotide binding; protein kinase activity; transcription factor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase regulator activity
Biological Process: negative regulation of fat cell differentiation; negative regulation of interleukin-10 biosynthetic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein amino acid phosphorylation; regulation of MAP kinase activity
Reference #:  Q92519 (UniProtKB)
Alt. Names/Synonyms: C5FW; FLJ57420; GS3955; TRB-2; TRB2; TRIB2; Tribbles homolog 2; tribbles homolog 2 (Drosophila)
Gene Symbols: TRIB2
Molecular weight: 38,801 Da
Basal Isoelectric point: 5.77  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

TRB2

Protein Structure Not Found.


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