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Protein Page:
MARK1 (human)

Overview
MARK1 a member of the CAMKL family of protein kinases. The MARK group of kinases is apparently involved in the control of cell polarity, microtubule stability and cancer. MARK1 forms a tight association with Tau in neurofibrillary tangles in Alzheimer disease tissue. Note: This description may include information from UniProtKB.
Protein type: CAMK group; CAMKL family; EC 2.7.11.1; EC 2.7.11.26; Kinase, protein; MARK subfamily; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 1q41
Cellular Component: cytoplasm; cytoskeleton; microtubule cytoskeleton; plasma membrane
Molecular Function: ATP binding; magnesium ion binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; protein serine/threonine kinase activity; tau-protein kinase activity
Biological Process: cytoskeleton organization and biogenesis; neuron migration; protein amino acid phosphorylation
Reference #:  Q9P0L2 (UniProtKB)
Alt. Names/Synonyms: KIAA1477; MAP/microtubule affinity-regulating kinase 1; MARK; MARK1; MGC126512; MGC126513; Serine/threonine-protein kinase MARK1
Gene Symbols: MARK1
Molecular weight: 89,003 Da
Basal Isoelectric point: 9.42  Predict pI for various phosphorylation states
CST Pathways:  Microtubule Dynamics
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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MARK1

Protein Structure Not Found.
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