a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Note: This description may include information from UniProtKB.
Protein type: Nuclear receptor co-regulator; Cell cycle regulation
Molecular Function: protein binding; protein kinase binding
Biological Process: cell division; mitosis; mitotic cell cycle G2/M transition DNA damage checkpoint; organ regeneration; positive regulation of fibroblast proliferation; positive regulation of transcription, DNA-dependent; Ras protein signal transduction; regulation of cyclin-dependent protein kinase activity; response to glucagon stimulus; viral reproduction
LTP: The number of records in which this modification site was determined using site-specific methods. SS methods include amino acid sequencing, site-directed mutagenesis, modification site-specific antibodies, specific MS strategies, etc.