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Protein Page:
MISR2 (human)

Overview
MISR2 On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.11.30; Kinase, protein; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; STKR family; TKL group; Type2 subfamily
Chromosomal Location of Human Ortholog: 12q13
Molecular Function: hormone binding; protein binding; receptor activity
Biological Process: sex differentiation; signal transduction
Disease: Persistent Mullerian Duct Syndrome, Types I And Ii
Reference #:  Q16671 (UniProtKB)
Alt. Names/Synonyms: AMH type II receptor; AMHR; AMHR2; Anti-Muellerian hormone type II receptor; Anti-Muellerian hormone type-2 receptor; anti-Mullerian hormone receptor, type II; MIS type II receptor; MISR2; MISRII; MRII; Mullerian inhibiting substance type II receptor
Gene Symbols: AMHR2
Molecular weight: 62,750 Da
Basal Isoelectric point: 5.53  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
Select Structure to View Below

MISR2

Protein Structure Not Found.


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