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Protein Page:
ROR1 (human)

Overview
ROR1 Tyrosine-protein kinase receptor whose role is not yet clear. Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); Ror family; TK group
Chromosomal Location of Human Ortholog: 1p31.3
Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane; receptor complex
Molecular Function: protein binding; transmembrane receptor protein tyrosine kinase activity; Wnt-protein binding
Reference #:  Q01973 (UniProtKB)
Alt. Names/Synonyms: dJ537F10.1; MGC99659; neurotrophic tyrosine kinase receptor-related 1; Neurotrophic tyrosine kinase, receptor-related 1; NTRKR1; receptor tyrosine kinase-like orphan receptor 1; ROR1; Tyrosine-protein kinase transmembrane receptor ROR1
Gene Symbols: ROR1
Molecular weight: 104,283 Da
Basal Isoelectric point: 6.76  Predict pI for various phosphorylation states
CST Pathways:  Tyrosine Kinases & Substrates
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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ROR1

Protein Structure Not Found.


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