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Protein Page:
SEC24A (human)

Overview
SEC24A Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. SEC24A is capable of forming heterodimers with SEC24B and SEC24C. Interacts with TMED2. Expressed in fibroblasts, hepatocytes, and lymphocytes. Belongs to the SEC23/SEC24 family. SEC24 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: cytosol; endoplasmic reticulum membrane
Molecular Function: protein binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport
Reference #:  O95486 (UniProtKB)
Alt. Names/Synonyms: Protein transport protein Sec24A; SC24A; SEC24 family, member A (S. cerevisiae); SEC24 related gene family, member A; SEC24-related protein A; SEC24A
Gene Symbols: SEC24A
Molecular weight: 119,749 Da
Basal Isoelectric point: 7.58  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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SEC24A

Protein Structure Not Found.
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