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Protein Page:
PAX5 (human)

PAX5 May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. Interacts with DAXX. Binds DNA as a monomer. Binds TLE4. Note: This description may include information from UniProtKB.
Protein type: Oncoprotein
Chromosomal Location of Human Ortholog: 9p13.2
Cellular Component: cytosol; fibrillar center; intracellular membrane-bound organelle; nucleoplasm
Molecular Function: protein binding
Biological Process: humoral immune response; multicellular organismal development; organ morphogenesis; transcription from RNA polymerase II promoter
Disease: Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Reference #:  Q02548 (UniProtKB)
Alt. Names/Synonyms: B cell specific activator protein; B-cell lineage specific activator; B-cell-specific transcription factor; BSAP; paired box 5; paired box homeotic gene 5; Paired box protein Pax-5; PAX5; transcription factor PAX 5
Gene Symbols: PAX5
Molecular weight: 42,149 Da
Basal Isoelectric point: 9.08  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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