This tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing. Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. Note: This description may include information from UniProtKB.
Protein type: DDR family; EC 220.127.116.11; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group
Molecular Function: collagen binding; protein binding; transmembrane receptor protein tyrosine kinase activity
Biological Process: biomineral formation; cell adhesion; collagen fibril organization; extracellular matrix organization and biogenesis; peptidyl-tyrosine phosphorylation; positive regulation of fibroblast proliferation; positive regulation of osteoblast differentiation; positive regulation of protein kinase activity; positive regulation of transcription factor activity; protein amino acid autophosphorylation; regulation of bone mineralization; signal transduction