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Protein Page:
MRLC1 (human)

MRLC1 Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. Myosin is an hexamer of 2 heavy chains and 4 light chains. Smooth muscle tissues and in some, but not all, nonmuscle cells. 2 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Contractile; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20q11.23
Cellular Component: cytosol; muscle myosin complex
Molecular Function: structural constituent of muscle
Biological Process: muscle contraction; regulation of muscle contraction
Reference #:  P24844 (UniProtKB)
Alt. Names/Synonyms: 20 kDa myosin light chain; LC20; MGC3505; MLC-2C; MLC2; MRLC1; MYL9; myosin regulatory light chain 1; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light polypeptide 9; Myosin RLC; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; MYRL2
Gene Symbols: MYL9
Molecular weight: 19,827 Da
Basal Isoelectric point: 4.8  Predict pI for various phosphorylation states
CST Pathways:  Actin Dynamics  |  TGF-ß Signaling
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

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