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Protein Page:
Musashi-1 (human)

Overview
Musashi-1 RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 12q24
Molecular Function: RNA binding
Biological Process: nervous system development
Reference #:  O43347 (UniProtKB)
Alt. Names/Synonyms: MSI1; MSI1H; musashi 1; musashi homolog 1 (Drosophila); Musashi-1; RNA-binding protein Musashi homolog 1
Gene Symbols: MSI1
Molecular weight: 39,125 Da
Basal Isoelectric point: 7.7  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Musashi-1

Protein Structure Not Found.
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