Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage Cell Signaling Technology
HomeAbout PhosphoSiteUsing PhosphoSiteprivacy & cookiesCuration ProcessContact
logos LINCs Logo Mt Sinai Logo NIH Logo NCI Logo
Protein Page:
4E-BP3 (human)

4E-BP3 Regulates eIF4E activity by preventing its assembly into the eIF4F complex. EIF4EBP3 interacts with EIF4E. Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus. Belongs to the eIF4E-binding protein family. Note: This description may include information from UniProtKB.
Protein type: Translation; Translation initiation
Chromosomal Location of Human Ortholog: 5q31.3
Cellular Component: cytoplasm; membrane
Molecular Function: eukaryotic initiation factor 4E binding; protein binding
Biological Process: negative regulation of translational initiation
Reference #:  O60516 (UniProtKB)
Alt. Names/Synonyms: 4E-BP3; 4EBP3; eIF4E-binding protein 3; EIF4EBP3; eukaryotic initiation factor 4E-binding protein 3; eukaryotic translation initiation factor 4E binding protein 3; Eukaryotic translation initiation factor 4E-binding protein 3
Gene Symbols: EIF4EBP3
Molecular weight: 10,873 Da
Basal Isoelectric point: 4.37  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Scansite  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene