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Protein Page:
USP28 (human)

Overview
USP28 a peptidase of the C19 family. USP28 and FBXW7 regulate Myc protein stability in response to DNA damage. Two isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: EC 3.4.19.12; Protease; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 11q23
Cellular Component: cytoplasm; nucleolus; nucleoplasm; nucleus; protein complex
Molecular Function: protein binding; ubiquitin-specific protease activity
Biological Process: cell proliferation; DNA damage checkpoint; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; protein deubiquitination; Ras protein signal transduction; regulation of protein stability; response to DNA damage stimulus; response to ionizing radiation
Reference #:  Q96RU2 (UniProtKB)
Alt. Names/Synonyms: Deubiquitinating enzyme 28; KIAA1515; Ubiquitin carboxyl-terminal hydrolase 28; ubiquitin specific peptidase 28; ubiquitin specific protease 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28; UBP28; USP28
Gene Symbols: USP28
Molecular weight: 122,491 Da
Basal Isoelectric point: 5.1  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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USP28

Protein Structure Not Found.
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